Thursday, August 06, 2015

POZylation: a new approach to enhance nanoparticle diffusion through mucosal barriers

Nanoscale, 2015, 7,13671-13679
DOI: 10.1039/C5NR03178H, Paper
Open Access Open Access
Creative Commons Licence  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Edward D. H. Mansfield, Katy Sillence, Patrick Hole, Adrian C. Williams, Vitaliy V. Khutoryanskiy
The permeation of thiolated silica nanoparticles through porcine gastric mucosa can be significantly enhanced by their functionalization with either 5 kDa poly(2-ethyl-2-oxazoline) or poly(ethylene glycol). The enhancement of nanoparticle permeability through mucus gel is due to the "stealth" properties of these polymers.
The content of this RSS Feed (c) The Royal Society of Chemistry


Click for full article

No comments:

Post a Comment