Nanoparticle Distribution during Systemic Inflammation is Size-Dependent and Organ-Specific

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR03626G, Paper

Kun-Hung Chen, David J. Lundy, Elsie Khai-Woon Toh, Chien-Hsi Chen, Crystal Hsin-ling Shih, Peilin Chen, Huan-Cheng Chang, James J. Lai, Patrick Stayton, Allan Hoffman , Patrick C.H. Hsieh
This study comprehensively investigates the changing biodistribution of fluorescent-labelled polystyrene latex bead nanoparticles in a mouse model of inflammation. Since inflammation alters systemic circulatory properties, increases vessel permeability and modulates...
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