Monday, August 03, 2015

Evaluation of nanoparticle delivered cisplatin in beagles

Nanoscale, 2015, Advance Article
DOI: 10.1039/C5NR03447G, Communication
Brittany Feldhaeusser, Simon R. Platt, Sean Marrache, Nagesh Kolishetti, Rakesh K. Pathak, David J. Montgomery, Lisa R. Reno, Elizabeth Howerth, Shanta Dhar
A nanoparticle formulation of a modified Pt(IV)-prodrug of cisplatin, Platin-M, was studied in healthy adult beagles and in canine glioma and glioblastoma cell lines for exploration of safety and toxicity for its potential future applications.
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