Thursday, May 07, 2015

RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing

Nanoscale, 2015, 7,9083-9091
DOI: 10.1039/C4NR05742B, Paper
Joao Conde, Furong Tian, Yulan Hernandez, Chenchen Bao, Pedro V. Baptista, Daxiang Cui, Tobias Stoeger, Jesus M. de la Fuente
Multifunctional siRNA glyconanoparticles trigger apoptotic pathways with the expression of cell death receptors and caspases and simultaneously trigger specific oncogene silencing via activation of the RNA interference pathway.
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