Friday, May 01, 2015

Quantitative Description of Thermodynamic and Kinetic Properties of the Platelet factor 4/Heparin Bonds

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR02132D, Paper
Thi Huong Nguyen, Andreas Greinacher, Mihaela Delcea
Heparin is the most important antithrombotic drug in hospitals. It binds to the endogenous tetrameric protein platelet factor 4 (PF4) forming PF4/heparin complexes which may cause a severe immune-mediated adverse...
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