Wednesday, November 19, 2014

Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages




Nanoscale , 2015, Advance Article

DOI: 10.1039/C4NR03962A, Paper

Ryan A. Ortega, Whitney J. Barham, Bharat Kumar, Oleg Tikhomirov, Ian D. McFadden, Fiona E. Yull, Todd D. Giorgio

Mannosylated nanoparticles are capable of delivering nucleotide sequences to tumor associated macrophages (TAMs) and have enhanced in vivo uptake in TAMs.

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